Last Updated on 7 days by Simi Mudaliar
Are you looking for the best CBD for anxiety? Look no further! Cannabidiol has been a hot topic over the last decade, mainly because it got a wide range of therapeutic properties, including anxiety and pain relief. So, in this article, we’ll discuss everything you need to know about CBD for anxiety, including its efficacy, reliability, and safety.
CBD Oil, Isolates, and More! What is CBD Oil?
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Cannabidiol, aka CBD oil, is a phytocannabinoid found in various marijuana strains. Unlike its other fellow phytocannabinoids—delta-9 THC and delta-8 THC—CBD is not a psychoactive compound which means it won’t make you high.
We are at an age where people value their health and well-being. Hence there is this dire search to find effective and safe alternatives to conventional medicine. Of the many holistic forms of therapy researched by scientists, cannabidiol seems to be the most promising. Research shows that CBD oil does have a wide array of therapeutic benefits, can be incredibly effective, and has a wide safety margin. However, it is not an FDA-approved drug, so it’s important to exercise caution when consuming CBD isolates, CBD gummies, etc.
CBD for Depression and Anxiety: Does it Really Work?
Understanding the pharmacokinetics of CBD is essential when defending its potential as an anxiolytic substance. Now the pharmacology surrounding cannabidiol is complex, and to this day, the science of its mechanism of action remains unclear. That said, we are moving to an age where CBD concentrates have become increasingly popular amongst members of the scientific community. So below, I will briefly touch upon the current research surrounding cannabidiol pharmacokinetics.
Cannabidiol acts on multiple pathways binding specifically to CB2 and CB1 receptors found throughout the body. When administered at high levels, cannabidiol acts directly on a class of receptors known as 5-HT, which activates serotonin receptors called 5-HT1A (hydroxytryptamine). And when these receptors activate, they bind to the neurotransmitter serotonin, which plays many physiological roles, including mood regulation, pain relief, memory, and learning.
As mentioned, there are many different pathways cannabidiol may take to produce anxiolytic in mammalian species. When consumed, cannabidiol acts on GABA-A receptors, enhancing its binding capabilities to the neurotransmitter GABA. Briefly, the GABA neurotransmitter plays a significant role in modulating the anxiety response in people. Increasing its potential to bind to the GABA-A receptors subsequently leads to a calming effect that reduces anxiety and improves sleep. Many anti-anxiety drugs act on this mechanism, including diazepam (aka Valium) and barbiturates.
Full Spectrum CBD Dosage for Anxiety Relief
Getting the dosage for CBD isolates right is incredibly niggly! First, I’d like to clarify that CBD is not regulated or registered under the FDA; hence, many of the recommended dosages you may see online are subjective and are in no way guaranteed to get you the results you need. We recommend speaking to your doctor before deciding to use CBD gummies for anxiety or full-spectrum CBD oils. Medical cannabis doctors who practice holistic medicine or alternative medicine can often provide their patients with an accurate off-label CBD dosage.
Disclaimer aside, I still did look into some recent studies published in various scientific journals to determine what their take was on CBD dosage in people. Here’s what I found:
In 2019 scientists conducted a case study to determine if CBD isolates could benefit people that presented with sleep or anxiety complaints. The study consisted of 72 adult patients who received CBD doses of 25 mg per day in the form of a capsule. Some patients received CBD doses of 50 mg per day or 75 mg per day. The result demonstrated that anxiety scores decreased in 79.2% of patients within the first month of CBD administration. As well, sleep scores improved in 66.7% of patients who presented within the first month.
Another more recent study researched in 2020 conducted a systematic review evaluating the efficacy and safety of cannabidiol isolates and concentrated in a human trial. Since this is a systematic review, the reviewers evaluated over 25 studies, including controlled clinical trials, to determine the efficacy of CBD isolates as a form of relieving anxiety in people. Of the 25 studies, 11 of them assessed CBD for anxiety in people. Within these 11 studies, participants were administered varying doses of CBD ranging from 150 mg to 900 mg (single dose). It appears that patients with a generalized anxiety disorder or general anxiety who consumed oral CBD capsules at 600 mg and 300 mg had reduced anxiety levels compared to the placebo.
CBD for Anxiety: The Best CBD Oil Products for You
Reliable CBD products, let alone CBD edibles are hard to come by! When searching for what’s the best CBD oil products for you, we highly recommend researching the company and analyzing the lab certificates of each product. So what are some key factors to keep in mind when searching for the best CBD products?
- Free from Harm: CBD is extracted from industrial hemp plants. Through the growing process, the hemp plant can absorb various chemicals, pesticides, and heavy metals. When picking a CBD product, it’s important to ensure that the hemp plant was grown in a pesticide-free environment.
- Lab Certification! A reliable CBD company will openly provide the latest lab certificates of their products. These certificates test for both heavy metals and pesticides.
Plain Jane CBD Gummies for Social Anxiety Disorder and Sleep
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